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Tell your doctor or pharmacist if you are taking or if you are planning to take any over-the-counter or prescription medications or dietary supplements with gastrointestinal anticholinergics or antispasmodics. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed. The following drugs and drug classes interact with gastrointestinal anticholinergics or antispasmodics.
Amantadine (eg, Symmetrel)
MAO Inhibitors (eg, Phenelzine)
Antacids (eg, Maalox)
Meperidine (eg, Demerol)
Anticholinergics, other (eg, bella donna alkaloids)
Metoclopramide (eg, Reglan)
Nitrates (eg, Nitroglycerin)
Benzodiazepines (eg, Diazepam)
Phenothiazines (eg, Promethazine)
Beta Blockers (eg, Atenolol)
Side Effects
Every drug is capable of producing side effects. Many anticholinergic or antispasmodic users experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:
Digestive Tract: Nausea; vomiting; bloating; constipation; abdominal pain; appetite loss; difficulty swallowing.
Despite the fact that there is no specific cure for multiple sclerosis in present, existing treatments are effective in slowing down the progression rate of the disease and preventing the development of further complications. Considering the fact that most of the effects of multiple sclerosis are irreversible, it is imperative to timely diagnose the disease and begin the administration of the appropriate course of medications. With the right treatment and with the aid of supportive therapies (physiotherapy and kinetotherapy), patients with multiple sclerosis can regain control of their bodies and live normal, active lives.
The medications available today are used to accomplish a series of goals in patients with multiple sclerosis: some medication treatments are aimed at slowing the progression rate of the disease, while others are aimed at ameliorating its generated symptoms and prolonging the periods of remission. The medications that are nowadays extensively used to delay and control symptomatic flare-ups among patients with multiple sclerosis are known as "ABC drugs". This category of medications consists of Avonex, Betaseron and Copaxone.
The so called ABC drugs are crucial in the treatment of multiple sclerosis, as they reduce the intensity, duration and frequency of the immune system's attacks on healthy nervous cells. These medications act by triggering a series of biologic mechanisms that decrease the autoimmune response of the body. Prescribed in the appropriate dose, each of these previously mentioned multiple sclerosis medications can reduce the frequency and intensity of specific neurological symptoms by up to 30 percent.
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